On January 1st, new rules from the Florida Wildlife Commission went into effect that govern the ownership of exotic animals. The FWC's notice detailing the changes(pdf) is available here. Some of the requirements are described here at Wakulla.com. Many of the requirements deal with Class I wildlife, which includes the animals that pose a significant danger to people. Anyone who possesses a Class I wildlife permit, with certain exceptions, must have a minimum of 5 acres of property. Additionally, facilities housing Class I captive wildlife cannot be in areas zoned solely for residential use.
Additionally, there are new requirements for people who keep six "reptiles of concern." As reported in the Sun-Sentinel, the Florida Wildlife Commission hopes the rules will help them keep track of on Burmese pythons, reticulated pythons, African rocky pythons, amethystine or scrub pythons, green anacondas and Nile monitor lizards. The new rules require permits, fees, and microchipping for identification.
More information on permits is available here at FWC's website.