Wednesday, January 23, 2008
Goodbye to LD50?
The Animal Welfare Information Center has a blog that collects a number of interesting stories. In recent days there was a post on the slow pace of adopting alternatives to animal testing. However, today the AWIC blog posted a link (that ultimately tracks back to an article at The Scientist's blog) detailing scientist recommendations to eliminate the lethal dose 50 (LD50) test, which involves literally measuring the amount of a toxic substance required to kill 50% of an animal test population. The call for drug companies to abandon the LD50 is based on a report in an upcoming journal of Regulatory Toxicology and Pharmacology.